MODEL QUESTION PAPER
SECOND PROFESSIONAL MBBS DEGREE
EXAMINATION
PHARMACOLOGY PAPER I
(NEW SCHEME)
Time: 2 hours
Maximummarks: 40
Answer all
questions.
I. Name the following
1. DOC for
petit mal epilepsy
2. Drug
producing phocomelia
3.
Cerebroselective anticholinesterase
4. One 5HT3
antagonist
5.
Antidepressant effective in chronic pain
6. A Clot
specific fibrinolytic agent
7. DOC for
anaphylactic shock
8. The
diuretic used in cerebral edema
9.
Transdermal patch used in angina pectoris
10. Shortest
acting cardio selective beta blocker
(½ x10= 5 marks)
II. Give the rationale for use of
following drugs
a.
Sumatriptan in acute attack of migraine
b.
Promethazine in motion sickness
c.
Haloperidol in acute schizophrenia
d.
Fluticasone inhalation in bronchial asthma (1x4 = 4marks)
III. Write two uses and two adverse
effects of the following drugs
a) Lithium
b) Amlodipine
c) Verapamil
d)
Neostigmine (1 x 4 = 4 marks)
IV. Enumerate 4 groups of antihypertensives with one
example for each. Mention 4 drugs
safe for use
in pregnancy. Write the pharmacological action, adverse effects and drug
interaction
of any one antihypertensive (2+1+ 2= 5marks)
V. Read the clinical problem and
answer the following questions
Ramesh, 28
years was administered an injection of Adrenaline with Lignocaine at base of
his
thumb for nail
extraction. Later he developed severe gangrene of thumb
a. Why has
gangrene developed? How could this have been avoided?
b. Write the
mechanism and pharmacological actions of adrenaline and lignocaine
c. List the
other two surface anaesthetics and write their adverse effects
d. Write the
cardiac use of lignocaine with dose and rationale. (1+2+1+1=5 marks)
VI. Choose the appropriate drug and
justify
a. Dopamine/
adrenaline in cardiogenic shock
b. Diazepam/
alprazolam in depressed person with anxiety
c. L-dopa/
trihexyphenidyl in drug induced parkinsonism
d. Ketamine /
Fentanyl in dissociative anaesthesia
e. Digoxin/
adenosine in atrial fibrillation
(1 x 5 = 5 marks)
VII. Write briefly on
a. Uses and
adverse effects of skeletal muscle relaxants
b.
Teratogenicity
c. Ketamine
d.
Chlorpromazine
(3 x 4 = 12marks)
