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Saturday 6 October 2012

BIOCHEMISTRY PAPER 1-MODEL QN-KUHS-2011


MODEL QUESTION PAPER
First Professional MBBS Degree Examination
Paper - I BIOCHEMISTRY
Time: 3 hrs                                                                                         Max marks: 50
Instructions:
• Draw diagrams wherever necessary
• Answer all questions.
1. Name the sulphur containing amino acid. Discuss metabolism of
the essential amino acid of this group and add a note on associate
inborn errors.                                                                                       (1+5+4=10 marks)
Discuss the following:
2. Complication of Diabetes mellitus
3. Components and sequence of reactions occur in Electron transport
chain.                                                                                                   (2x5 =10 marks)
Write short notes on:
4. Structure of human insulin.
5. Structure of bio membrane.
6. Fatty acid synthase enzyme complex.
7. Glycation of haemoglobin and it's significances.
8. What is the Normal serum cholesterol? Why HDL & LDL
cholesterol are known as good and bad cholesterol respectively ?( 5x3 =15 marks)
Write briefly:
9. Key enzymes of gluconeogenesis.
10. Energy expenditure in Urea cycle.
11. Importance of Carnitine in lipid metabolism
12. Deficient enzyme and clinical features in galactosemia.
13. What is the biochemical basis of fatty liver in alcoholism?      (5x2 =10 marks)
Give precise answers:
14. What is the basis of curdling of milk?
15. Mention any four fate of acetyl CoA.
16. Mention any two functions of phospholipids.
17. Mention any two enzymes used as therapeutic agents
18. Why sample for glucose estimation is collected in a fluoride
bottle?                                                                                                 (5x1 =5 marks)